Nickel-catalyzed four-component connection of oraganoaluminium (organozinc), isoprene, aldehydes and amines: stereo- and regioselective synthesis of trisubstituted (E)-homoallylamines.
نویسندگان
چکیده
Ni(acac)2 catalyzes the four-component connection reaction of trimethylaluminium (or diphenylzinc), isoprene, aromatic aldehydes and p-anisidine in this order and provides (E)-1-aryl-1-(p-methoxyphenyl)amino-3-methyl-3-hexenes (or (E)-1-aryl-1-(p-methoxyphenyl)amino-3-methyl-5-phenyl-3-pentenes) selectively in good yield.
منابع مشابه
cis-stereoselective nickel-catalyzed cyclization/alkylation and arylation reactions of allenyl-aldehydes and -ketones with organozinc reagents.
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ورودعنوان ژورنال:
- Chemical communications
دوره 37 شماره
صفحات -
تاریخ انتشار 2005